Endocrine Abstracts

Introduction: Pituitary apoplexy (PA) is a syndrome caused by acute hemorrhage or infarction of the pituitary gland, generally within a pituitary adenoma. Early diagnosis of PA and a multidisciplinary approach are essential for the timely treatment of pan-hypopituitarism and prevention of severe neurologic complications.Observation: We report the cases of two men aged 46 and 53 years old with pituitary apoplexy. Apoplexy occurred in one patient with pre-...

Introduction: Growth retardation is a frequent reason for consultation in endocrinology, it is often isolated but it can integrate into a syndromic context. Its management requires a rigorous diagnostic procedure conducted in a specialized environment. The aim of our work is to analyze the epidemiological, clinical and etiological profile of RSP occurring in a syndromic setting.Materials and methods: This is a retrospective study of 68 cases among 192 pa...

Introduction: Growth hormone deficiency (GHD) associated with a congenital malformation of the hypothalamic-pituitary axis is rare. It can be isolated or part of a combined pituitary deficiency. The purpose of our work is to describe the clinical picture in which between GH deficiency in children.Materials and methods: This is a retrospective study of 18 cases among 192 patients consulting for growth retardation, conducted in the Endocrinology Diabetolog...

Introduction: Acromegaly is a quite rare and insidious disease caused by the oversecretion of growth hormone and subsequently insulin - like growth factor 1. Recent studies have demonstrated an increased co-existence of different thyroid lesions with acromegaly. However the data concerning this co-occurrence remains a matter of debate. The purpose of this study is to shed light on the different thyroid lesions concerning the patients with acromegaly who are followed up in the ...

Introduction: Gestational diabetes and maternal obesity have long been regarded as risk factors for pregnancy. The amount of weight gained during pregnancy can affect the immediate and future health of a woman and her infant [1]. The objective of our study is to evaluate the impact of maternal weight status on the glycemic profile of women followed for gestational diabetes.Materials and methods: This is a retrospective study over three years, including 2...

Introduction: Strict metabolic control is the main purpose in the management of type 1 diabetes in order to prevent patients from macro or microvascular complications. The therapy of type 1 diabetes was optimized by the basal-bolus regimens with multiple daily injections in addition to the educational programs such as flexible insulin therapy. Nevertheless, despite all those therapeutic approaches, the metabolic control is not always obtained. The specific aim of our study is ...

Introduction: The non-compliance to treatment is defined as the lack of adequacy between patients’ behaviors in taking medication, following a diet, and/or executing lifestyle changes, and medical prescriptions. It is a major cause of therapeutic failure that puts into question the real efficiency of medical care. The objective of this study was to evaluate the therapeutic compliance degree in diabetic patients and to determine the different factors and issues complicatin...

Introduction: Maturity Onset Diabetes of the Young (MODY) is a monogenic form of non-insulin-dependent diabetes that classically presents in a lean individual with non ketotic hyperglycaemia and an autosomal dominant inheritance pattern. The diagnosis remains a challenge and may be made by careful clinical evaluation, but exact sub-typing is possible only by genetic analysis.Materials and methods: This is a prospective data analysis in the diabetology-en...

Introduction: Hyperuricemia is associated with an increase in cardiovascular risk and complications of type 2 diabetes (1). The aim of this study is to establish a possible link between lipid profile and hyperuricemia.Method: A total of 321 patients with type 2 diabetes were included in our study. Clinical and par clinical data were collected from patients’ medical records. The lipid profile includes low density lipoprotein (LDL), high density lipop...

Introduction: Turner syndrome occurs in one out of every 2,500 to 3,000 live female births. The syndrome is characterized by the partial or complete absence of one X chromosome (45,X karyotype)(1). Patients with Turner syndrome are at risk of congenital heart defects, and is defined by the association of a dysmorphic and malformative syndrome, the main elements of which are small size and gonadal dysgenesis(2).Methodology: Descripti...